Main Sequence portfolio companies
Main Sequence is a deep tech venture fund founded by CSIRO in 2017. It backs companies built on science, from space and robotics to food and health. These are the companies it lists on its own site, newest investment first.
58 companies · 11 hiring now
2026 · 3
Andromeda
Where technology meets empathy – pioneering the future of human-robot interaction.
Cortisonic
Physics-Powered Learning Machines.
DeteQT
Quantum sensors for magnetic field-aware intelligence
2025 · 4
Breaker
Breaker leverages AI, including LLMs, at the edge to optimize robotics deployment and control, starting with drones for defense and beyond.
Currus Biologics
Developing the next generation of CAR-T cell therapies to treat solid cancers.
Electralith
The cleanest and most cost effective DLE technology; all in a single step process
Terria
Terria makes it easy to build advanced maps and digital twins.
2024 · 2
Diraq
Delivering revolutionary quantum computing technology to the world.
Xefco
Advanced plasma technology to enable sustainable, water-free textile dyeing and finishing.
2023 · 1
Year not listed · 48
Advanced Navigation
Chris is building autonomous navigation solutions.
21 roles in Australia
Amber Electric
Wholesale electricity provider with smart electricity options
5 roles in Australia
Arkeus AI
Accelerating decision making through the fusion of optics and autonomy.
Avarni
Automate your carbon accounting and emissions management
Baraja
Building revolutionary LiDAR to support revolutionary thinkers
1 role in Australia
Castlepoint Systems
Manage information everywhere
Cauldron
Asia-Pacific’s first manufacturing launchpad to enable precision fermentation at global scale
Coviu
The future of telehealth
Cylite
Redefining and improving the future of eye health
Eden Brew
Cow-less, sustainable and nutritious dairy
Emesent
Autonomous 3D mapping and data visualization
13 open roles
Endua
Day and night renewable energy
17 open roles
EVERY
Powerful protein, without the animal
2 open roles
Fivecast
Enabling a safer world with AI
Gilmour Space Technologies
Launching satellites to space, efficiently
Inventia Life Science
Revolutionising 3D cell biology
JDoodle
Programming ecosystem for the AI era
Kapiche
Supercharging actionable customer insights
Kasada
Stopping bot attacks that others can’t
1 open role
Levur
Brewing a Sustainable Alternative to Palm Oil
Loam Bio
Microbial technology capturing carbon in agricultural soils
Lumachain
AI-powered platform to transform global protein and food supply chains.
MGA Thermal
Energy storage blocks for a zero-carbon future
milliBeam
Developing semiconductor integrated circuits and chipsets for mmWave 5G radios
Morse Micro
Smarter, farther and better Wi-Fi with HaLow Microprocessors
4 roles in Australia
Myriota
Low-cost, low-power satellite connectivity
Nourish Ingredients
The missing piece for alternative meats - fats
Number 8 Bio
Decarbonising the planet with synthetic biology
Pending AI
Ushering in a new paradigm of medicinal innovation with scalable artificial intelligence and quantum mechanics
Plotlogic
The future of natural resource mining: greater recovery, less waste
Practera
Powering experiential learning
Presien
Presien is an AI vision company solving real heavy industry challenges, from quality assurance and control to security and safety. Presien improves how heavy industry goes to work.
Prospection
Harnessing real world data to improve patient outcomes
Q-CTRL
Making quantum technology useful
12 roles in Australia
Quantum Brilliance
Enabling ubiquitous quantum computing
Quasar Satellite Technologies
Ground Infrastructure for space
7 open roles
QuintessenceLabs
The future of security in a quantum-driven world
Rainstick
Combining traditional knowledge with modern technology for plants and fungi
Regrow
Reliant, scalable and sustainable crop insights
RIOS
Reinventing factory automation with robotics and AI
Samsara Eco
Infinite recycling to end plastic pollution
Skykraft
Space-enabled air traffic management
SunDrive
Building a sustainable future with the world's most efficient solar cell
Trellis Data
Making artificial intelligence explainable
ULUU
Reviving the world with regenerative material
2 open roles
v2food
A new and sustainable version of meat
Varden
Sustainable packaging for a sustainable future
XYLO
Psychedelic medicine to treat mental illness
Other funds
Each company is listed as the funds list it on their own portfolio pages, read daily: a company two funds back appears once, with both. The year is when each fund lists its first investment. A company page is indexed once an editor has checked its summary.